2'-Fucosyllactose CAS#41263-94-9

Products Description of 2'-Fucosyllactose CAS#41263-94-9

2’-Fucosyllactose (2’-FL), launched by BASF’s Newtrition® brand for human nutrition in early 2019, is one of the most abundant human milk oligosaccharides (HMOs) available for infant nutrition applications. HMOs are a unique group of carbohydrates naturally present in breast milk and represent the third most abundant solid component of breast milk after fat and lactose.

2’-Fucosyllactose is produced through microbial fermentation using genetically modified Escherichia coli strains. It can be incorporated into various nutritional products, including stage 1 infant formulas (0–1 year), stage 2 infant formulas (6 months–1 year), formulas designed for special dietary needs, and nutritional supplements for toddlers.

Research indicates that 2’-FL helps support a healthy gut microbiota and immune system development, may contribute to the prevention of allergic conditions, and plays an important role in maintaining normal brain function and cognitive development. Additionally, 2’-fucosyllactose is considered a promising ingredient for digestive health due to its potential ability to help regulate mucosal inflammation.

Product Application of 2'-Fucosyllactose CAS#41263-94-9

Breastfeeding is considered the optimal approach for infant nutrition. Natural human breast milk from most women contains 2'-fucosyllactose (2'-FL), although infants are not yet able to synthesize fucosylated human milk oligosaccharides (HMOs) on their own.

2'-FL is one of the major oligosaccharides found in human milk but is absent from bovine milk. Currently, commercially produced 2'-FL provides a way to supplement this important component in infant nutrition products.

As a prebiotic, 2'-FL supports beneficial intestinal bacteria, which metabolize it into short-chain fatty acids. These metabolites serve as an energy source for colon cells and help promote sodium and water absorption. Therefore, conventional infant formulas used as breast milk substitutes may lack this naturally occurring component that is abundant in human milk.

Most infants are naturally exposed to 2'-FL through breastfeeding but not to 2'-FL produced through alternative manufacturing processes. Commercially produced 2'-FL, such as Jennewein 2'-FL, is chemically equivalent to the naturally occurring 2'-FL found in human breast milk.