Polysorbate 20 CAS#9005-64-5
Effective Stabilizing Properties: Tween 20 is commonly used as a stabilizer during the production of biological products and in their final formulations.
Broad Solvent Compatibility: It is soluble in water, ethanol, methanol, and ethyl acetate, making it compatible with a variety of solvents.
Distinctive Physical Properties: Tween 20 is a clear, yellow to amber oily liquid with a characteristic odor and a faint, bitter taste, with a relative density of 1.08–1.13 and a boiling point of 321°C.
Established Manufacturing Process: Tween 20 is produced by reacting sorbitan monolaurate with ethylene oxide, providing a defined chemical production route.
Products Description of Polysorbate 20 CAS#9005-64-5
Polysorbate 20, also known as Tween 20, is a surfactant that appears as a clear, yellow to amber oily liquid with a characteristic odor and a slightly bitter taste. It is widely used as a stabilizer during the manufacturing process and in the final formulations of biological products. Polysorbate 20 is manufactured through the reaction of sorbitan monolaurate with ethylene oxide. It has a relative density of 1.08–1.13 and a boiling point of 321°C. It is soluble in water, ethanol, methanol, and ethyl acetate, but insoluble in mineral oil and petroleum ether.
Polysorbate 20 Chemical Properties
| Melting point | 98.9 °C (decomp) |
| Boiling point | 100 °C |
| density | 1.11 g/mL at 20 °C |
| vapor pressure | <1.4 hPa (20 °C) |
| refractive index | n20/D 1.468(lit.) |
| FEMA | 2915 | POLYSORBATE 20 |
| Fp | >230 °F |
| storage temp. | Store below +30°C. |
| solubility | 100 g/L |
| form | viscous liquid |
| Specific Gravity | 1.090～1.130 (20/20℃) |
| color | Amber |
| PH | 6-8 (50g/l, H2O, 20℃) |
| Odor | mild alcohol odor |
| PH Range | 7 |
| Odor Type | alcoholic |
| Water Solubility | 100 g/L |
| Hydrophilic-Lipophilic Balance (HLB) | 16.7 |
| Stability: | Stable. Incompatible with strong oxidizing agents. |
| EPA Substance Registry System | Polysorbate 20 (9005-64-5) |
| Hazard Codes | Xi |
| Risk Statements | 22-36/37/38-37/38-41 |
| Safety Statements | 24/25-36/37/39-36-26 |
| WGK Germany | 1 |
| RTECS | TR7400000 |
| F | 46318 |
| TSCA | Yes |
| HS Code | 34021300 |
| Hazardous Substances Data | 9005-64-5(Hazardous Substances Data) |
| Toxicity | LD50 orally in Rabbit: 38900 mg/kg |
Product Application of Polysorbate 20 CAS#9005-64-5
Tween 20 is an oil-in-water emulsifier with a wide range of functions, including solubilization, diffusion, stabilization, lubrication, and antistatic properties. In the petroleum industry, it can serve as a paraffin inhibitor to remove wax deposits from oil wells. It can also act as a viscosity reducer, lowering crude oil viscosity, increasing oil well production, and improving transportation efficiency. In pharmaceutical and daily chemical applications, Tween 20 is used as a solubilizer, penetrant, and dispersant in medicines and cosmetics. Additionally, due to its rust-preventive and lubricating properties, it is used in the formulation of rust-preventive lubricating oils, as well as rust-removing and degreasing oils.
