2-Chloro-6-aminopyrazine CAS#33332-28-4

Important Pharmaceutical Intermediate: 2-Amino-6-chloropyrazine is widely used in the synthesis of A2B adenosine receptor antagonists and other bioactive compounds.
Stable Physical and Chemical Properties: The compound exhibits reliable thermal and chemical stability with defined melting and boiling points suitable for research and industrial applications.
Versatile Solubility Characteristics: It is slightly soluble in water and readily soluble in hot methanol, supporting flexible use in various synthesis processes.
High Applicability in Chemical Research: As a disubstituted pyrazine derivative, it serves as a valuable building block in pharmaceutical and fine chemical development.

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Product Details

2-Amino-6-chloropyrazine CAS#33332-28-4

2-Amino-6-chloropyrazine is a disubstituted pyrazine compound commonly used in the synthesis of A2B adenosine receptor antagonists and various other bioactive compounds. Its molecular formula is C4H4ClN3, with a molecular weight of 129.55 and CAS Registry Number 33332-28-4.

This compound appears as a colorless to grayish-white solid, with a density of 1.4 ± 0.1 g/cm³. It has a melting point of 150–152 °C, a boiling point of 282.8 ± 35.0 °C, and a flash point of 124.8 ± 25.9 °C. It is slightly soluble in water and readily soluble in hot methanol.

2-Chloro-6-aminopyrazine CAS#33332-28-4

2-Chloro-6-aminopyrazine Chemical Properties

Melting point	150-152°C
Boiling point	282.8±35.0 °C(Predicted)
density	1.437±0.06 g/cm3(Predicted)
storage temp.	under inert gas (nitrogen or Argon) at 2–8 °C
solubility	Soluble in dimethyl sulfoxide and methanol.
form	Solid
pka	0.89±0.10(Predicted)
color	Purple
LogP	0.95
CAS DataBase Reference	33332-28-4(CAS DataBase Reference)
EPA Substance Registry System	2-Amino-6-chloropyrazine (33332-28-4)
Hazard Codes	Xi,Xn
Risk Statements	36/37/38-41-22
Safety Statements	26-36/37/39-60-37
TSCA	Yes
HazardClass	IRRITANT
HS Code	29339900

2-Chloro-6-aminopyrazine CAS#33332-28-4

Product Application of 2-Chloro-6-aminopyrazine CAS#33332-28-4

2-Amino-6-chloropyrazine is commonly used as an intermediate in organic synthesis and pharmaceutical manufacturing. It is primarily applied in laboratory research and development, as well as in chemical and pharmaceutical production processes.

2-Chloro-6-aminopyrazine CAS#33332-28-4