Chloroacetyl Chloride CAS#79-04-9

Highly Reactive Acylation Reagent: Exhibits strong chemical activity and serves as an efficient acylation reagent for various organic synthesis reactions.
Broad Application in Organic Synthesis: Can react with diverse compounds such as naphthalene, cyclopropane, and ethylene, offering versatility in chemical transformations.
Excellent Solubility in Organic Solvents: Shows good solubility in benzene, carbon tetrachloride, ether, and chloroform, facilitating its use in organic reaction systems.
Useful Intermediate for Chemical Production: Can be converted into valuable compounds such as 2-chloroethanol through reduction reactions, expanding its application potential in chemical synthesis.

Contact Now E-Mail Telephone WhatsApp

Product Details

Products Description of Chloroacetyl Chloride CAS#79-04-9

Chloroacetyl chloride is a colorless to slightly yellow liquid with strong irritant properties. It is soluble in organic solvents such as benzene, carbon tetrachloride, ether, and chloroform. Due to its toxic nature, it may cause irritation to the eyes and mucous membranes and should be handled with appropriate precautions.

With highly active chemical properties, chloroacetyl chloride readily decomposes in the presence of water and alcohol. It is widely used as an acylation reagent in organic synthesis and can react with various compounds, including naphthalene, cyclopropane, and ethylene. Additionally, it can be reduced by lithium aluminum tetrahydride in diethyl ether to produce 2-chloroethanol, further enhancing its value as a chemical intermediate.

Chloroacetyl Chloride CAS#79-04-9

Chloroacetyl chloride Chemical Properties

Melting point	−22 °C(lit.)
Boiling point	105-106 °C(lit.)
density	1.419 g/mL at 20 °C
vapor density	3.9 (vs air)
vapor pressure	60 mm Hg ( 41.5 °C)
refractive index	n20/D 1.453(lit.)
Fp	>100°C
storage temp.	Store at RT.
solubility	Miscible with ethyl ether, acetone, benzene and carbon tetrachloride.
form	Liquid
color	Clear colorless to slightly yellow
Odor	strong pungent odor
Water Solubility	reacts
FreezingPoint	-22.5℃
Sensitive	Moisture Sensitive
Merck	142067
BRN	605439
Exposure limits	ACGIH: TWA 0.05 ppm; STEL 0.15 ppm (Skin)
Exposure limits	NIOSH: IDLH 1.3 ppm; TWA 0.05 ppm(0.2 mg/m3)
Stability:	Stable. Incompatible with strong bases, alcohols, strong oxidizing agents. May react violently on exposure to water or moisture.
CAS DataBase Reference	79-04-9(CAS DataBase Reference)
NIST Chemistry Reference	Acetyl chloride, chloro-(79-04-9)
EPA Substance Registry System	Chloroacetyl chloride (79-04-9)
Hazard Codes	T,C,N
Risk Statements	14-23/24/25-35-48/23-50-29
Safety Statements	9-26-36/37/39-45-61-7/8
RIDADR	UN 1752 6.1/PG 1
WGK Germany	3
RTECS	AO6475000
TSCA	Yes
HazardClass	6.1
PackingGroup	I
HS Code	29159000
Hazardous Substances Data	79-04-9(Hazardous Substances Data)
IDLA	1.3 ppm (6 mg/m3)

Chloroacetyl Chloride CAS#79-04-9

Product Application of Chloroacetyl Chloride CAS#79-04-9

Chloroacetyl chloride is a key intermediate widely used in pesticide production. It can be utilized in the synthesis of various insecticides, such as dimethoate and omethoate, as well as fungicides including imazalil, metalaxyl, and oxamyl. It is also involved in the preparation of numerous herbicides, including alachlor, acetochlor, pretilachlor, butachlor, benzochlor, metolachlor, sulfaphos, and benzofenacet.

In addition, chloroacetyl chloride serves as an important pharmaceutical intermediate with broad applications in drug synthesis. It can be used to produce pharmaceutical compounds such as chlordiazepoxide, diazepam, nitrazepam, lidocaine, praziquantel, methocaine, ethothiazide, piperazepine, fluconazole, and econazole.

Chloroacetyl Chloride CAS#79-04-9