Piperazinone CAS#5625-67-2
Important Pharmaceutical Intermediate – 2-Piperazinone is an important aliphatic heterocyclic intermediate widely used in pharmaceutical applications.
Well-Defined Chemical Properties – 2-Piperazinone has a defined chemical formula of C₄H₈N₂O, a molecular weight of 100.12, and CAS number 5625-67-2, supporting reliable identification and application.
Stable Physical Characteristics – 2-Piperazinone has a melting point of 136–140°C, a boiling point of 307.1 ± 35.0°C at 760 mmHg, and a flash point of 166.3 ± 26.1°C.
Versatile Research Applications – Primarily used in biochemical research, 2-Piperazinone appears as a colorless solid at room temperature, facilitating handling and laboratory use.
Products Description of 2-Piperazinone CAS#5625-67-2
2-Piperazinone is a nitrogen-containing heterocyclic organic compound and an important aliphatic heterocyclic intermediate used in pharmaceutical applications. Its chemical formula is C₄H₈N₂O, with a molecular weight of 100.12 and CAS number 5625-67-2.
2-Piperazinone has a density of 1.1 ± 0.1 g/cm³, a melting point of 136–140°C, a boiling point of 307.1 ± 35.0°C at 760 mmHg, and a flash point of 166.3 ± 26.1°C. It is primarily used in biochemical research and appears as a colorless solid at room temperature.
2-Piperazinone Chemical Properties
| Melting point | 136-140 °C (lit.) |
| Boiling point | 164°C/5mmHg(lit.) |
| density | 1.053±0.06 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| solubility | Chloroform |
| form | Crystalline Powder |
| pka | 15.47±0.20(Predicted) |
| color | White to tan |
| Sensitive | Hygroscopic |
| Stability: | Stable, but may be light and moisture sensitive. Incompatible with oxidizing agents. |
| InChIKey | IWELDVXSEVIIGI-UHFFFAOYSA-N |
| CAS DataBase Reference | 5625-67-2(CAS DataBase Reference) |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38-43 |
| Safety Statements | 26-36/37 |
| RIDADR | 1759 |
| WGK Germany | 3 |
| HazardClass | 8 |
| PackingGroup | III |
| HS Code | 29349990 |
2-Piperazinone is an important intermediate in organic synthesis and the pharmaceutical industry. It is used in the synthesis of piperazine, norfloxacin, pipemidic acid, quinolones, and various pharmaceutical intermediates for drugs used to treat parasitic infections, tuberculosis, diabetes, and bacterial infections.
In addition, 2-Piperazinone serves as a raw material for a wide range of products, including textile dyeing and finishing auxiliaries, rubber vulcanization accelerators, antioxidants, preservatives, stabilizers, synthetic resins, synthetic fibers, and synthetic leather.
