2-Bromo-2-nitro-1,3-propanediol CAS#52-51-7
Good Solubility in Multiple Solvents – It is readily soluble in water, ethanol, propylene glycol, and ethyl acetate, ensuring versatile formulation compatibility.
Moderate Thermal Stability – The compound has a defined melting point range of 122–130°C, indicating stable physical properties.
Limited Oil and Organic Solvent Solubility – It is only slightly soluble in oil and sparingly soluble in solvents such as chloroform and acetone, supporting controlled application behavior.
High Applicability in Formulations – Its balanced solubility profile makes it suitable for use in antibacterial and related chemical formulations.
Products Description of Lopol (2-Bromo-2-nitro-1,3-propanediol)
Lopol, chemically known as 2-bromo-2-nitro-1,3-propanediol and also referred to as bromonitrol or antibacterial alcohol, is a white crystalline powder with a melting point of 122–130°C.
It is readily soluble in water, ethanol, propylene glycol, and ethyl acetate, slightly soluble in oil, and sparingly soluble in solvents such as chloroform and acetone.
Properties
| Density | 1.91 |
| Melting point | 124-129℃ |
| Boiling point | 358 °C at 760 mmHg |
| Refractive index | 1.574 |
| Flash Point | 170.3 °C |
| Vapour Pressure | 0.0±1.8 mmHg at 25°C |
| Precise Quality | 198.948 |
| PSA | 86.28 |
| logP | -0.1379 |
| Solubility | H2O: soluble100mg/mL, clear, colorless to faintly yellow |
| Appearance | White to slightly yellow crystals or crystalline powder |
| Storage | Ambient temperatures. |
| Chemical Properties | off-white crystalline powder |
| Physical Properties | Colorless, white, or pinkish crystals with a slight phenolic odor. On exposure to air it slowlybecomes light brown. |
| Color/Form | White to yellow |
| Contact Allergens | Bronopol is a preservative sometimes considered as aformaldehyde releaser. It was reported to be an allergenin cosmetics, cleaning agents, dairy workers, and alubricant jelly used for ultrasound examination. |
| Decomposition | The substance decomposes on heating or on burning producing toxic and corrosive fumes, including hydrogen bromide and nitrogen oxides. |
| Odor | Odorless |
| pKa | 12.02±0.10(Predicted) |
| Water Solubility | 25 g/100 mL (22 oC) |
| Spectral Properties | MASS: 75372 (NIST/EPA/MSDC Mass Spectral Database, 1990 version); 1023 Wiley |
| Stability | Stable. Hygroscopic. Incompatible with strong oxidizing agents, strong bases, strong reducing agents, acid chlorides and anhydrides, moisture. |
| StorageTemp | Inert atmosphere,Room Temperature |
Product Application of Bropol
Bropol is highly effective against a broad range of plant pathogenic bacteria and is mainly used as a seed treatment agent.
Due to its broad-spectrum antibacterial properties, it has been used as a disinfectant in the pharmaceutical industry since the 1960s. With the rapid development of the cosmetics industry, its good water solubility and strong antimicrobial activity have also promoted its widespread use as a cosmetic preservative.
In recent years, Bropol has been increasingly applied in feed, coatings, fur preservation, air conditioning circulating water treatment, oilfield injection water sterilization, and the disinfection of aircraft, vehicles, and ships, leading to continuously growing market demand.
